NIH R01 · 2025
Sensorimotor processing in the oculomotor system: moving targets and interceptive saccades
PROJECT SUMMARY Accurate interception of a moving object presents a significant challenge for the nervous system. The object’s continuous motion produces a lagged representation of its spatial location in the brain because retinal signals relayed to motor neurons traverse through diverse parallel pathways with varying integration times, conduction speeds, and synaptic delays. The brain therefore cannot utilize current retinal signals but must rely on its ability to estimate the object’s future location. Saccades are an effective motor system to study interception. The superior colliculus provides an established framework for investigating sensorimotor processes driving visually guided…
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