Gamage Lab

Upstate Medical University

OTHER BASIC SCIENCES

Syracuse · United States

NIH-funded
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Research focus

NIH R01 · 2024

Minor Cannabinoids and Terpenes: Preclinical Evaluation as Analgesics

PROJECT SUMMARY Throughout recorded history, humans have used natural products for medicinal purposes. With the onset of modern analytical and pharmaceutical methods, the active ingredients in some of these “natural remedies” were identified and became foundational chemicals in drug development efforts. Among the numerous examples, aspirin (bark of the willow tree), capsaicin (chili peppers), and opioids (opium poppy plant) are notable for their analgesic properties. Similar to these other natural products, Cannabis sativa has long been used for medicinal purposes, including pain relief. The cannabis plant (Cannabis sativa/indica) contains over 100 phytocannabinoids as well as over 500…

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