NIH R01 · 2025
Neurogenetic approaches to study directed behavior in Drosophila
PROJECT SUMMARY Temperature sensing is an important constituent of the somatosensory system and arguably one of the most ancient sensory modalities. Little is known about the central mechanisms that allow us to distinguish hot, cold, and noxious temperatures, or on how different thermal ranges become innately associated with either positive(“warm/cool”) or negative (“hot/cold”) hedonic valence in the brain. Our laboratory is addressing these fundamental questions by studying the circuit mechanisms underlying temperature sensing and preference in the fruit fly Drosophila. Supported by this grant, we have embarked in an effort to follow the full processing of temperature information in the…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.