NIH R01 · 2024
Host Cell Signaling Pathways Induced by Salmonella
PROJECT SUMMARY Salmonellosis continues to be a major Public Health challenge resulting in more than 300,000 death world- wide. In the US alone, Salmonella causes an estimated 1 million infections resulting in annual economic burden of $2.8 billion. Salmonella enterica encompasses multiple serovars that are associated with distinct pathogenic features and host specificities. Some serovars (e. g. S. Typhimurium) exhibit broad host specificity, cause self-limiting gastroenteritis, and are one of the most common causes of food-borne illnesses in the industrialized world. In contrast, other serovars such as S. Typhi exhibit remarkable host specificity limiting their ecology to the human host…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.