NIH R01 · 2024
Non-Invasive Single-Cell Morphometry and Tracking in Living Bacterial Biofilms
Project Summary/Abstract Biofilms are cohesive, multicellular microbial communities that are able to adhere to biotic or abiotic surfaces. The human microbiome contains numerous biofilm-forming bacterial species that help maintain normal human physiology. On the other hand, more than half of the 1.7 million hospital-acquired infections in the US are caused by biofilm-forming bacterial pathogens. The biofilm lifestyle is advantageous, because phenotypic diversity and coordination of cellular behaviors within biofilms provide bacterial populations with emergent capabilities beyond those of individual cells. For example, biofilms are orders of magnitude more tolerant towards physical,…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.