NIH R01 · 2025
Low-dose contrast enhanced fast pediatric brain MRI
Project Summary: Brain MRIs are widely used in children for diagnosis and treatment monitoring. A typical exam comprises multiple sequences with different contrast preparations, and often requires 20+ minutes to complete. Potential motion during such lengthy acquisitions necessitates sedation or anesthesia. However, repeated sedation or anesthesia in children increase the risk of long-term detrimental effects on cognitive development. 40% of these pediatric scans also require gadolinium (Gd) based contrast agent (GBCA) administration. It has been recently shown that Gd is retained in the brain and body, which may be particularly harmful to children since their developing brains are more…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.