Gaffo Lab

University of Alabama at Birmingham

INTERNAL MEDICINE/MEDICINE

Birmingham · United States

NIH-funded
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NIH R01 · 2025

Gout Epidemiology in Chronic Kidney Disease: Transition to End-stage Kidney Disease and Impact of Renal Transplant

PROJECT SUMMARY Gout coexisting with advanced chronic kidney disease (CKD) poses a complex and under-researched medical challenge. There is scant evidence and an important knowledge gap to guide gout management in patients transitioning from advanced CKD to end-stage kidney disease (ESKD), where dialysis or kidney transplantation (KT) becomes necessary. Understanding the burden of gout during the transition from non- dialysis CKD to ESKD and subsequently to KT is essential for optimizing treatment strategies and improving patient outcomes. This research, utilizing data from the United States Renal Data System (USRDS), aims to explore the evolution of gout burden (including flares and…

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