NIH R01 · 2025
Novel physiomarkers of high-risk labored breathing for advance warning of clinical deterioration
Respiratory failure is common (800,000 yearly intubations), life-threatening (35% mortality rate), and costly (12% of all hospital costs). Advance warning of respiratory deterioration may trigger timely treatment, but it is difficult to predict an imminent deterioration despite advanced datasets and analytics. To address this problem, the proposed project will address a critical gap in contemporary physiological monitoring: the inability to quantify labored breathing. Breathing patterns (or respiratory kinematics) contain vital prognostic information that is not captured by conventional monitoring. There has been no way to quantify this information in a clinical practice setting. As such,…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.