Fyfe-Johnson Lab

Washington State University

NONE

Pullman · United States

NIH-funded
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NIH R01 · 2025

Childhood Obesity: the role of the gut Microbiome, outdoor Time, and Stress(COMETS)

PROJECT SUMMARY/ABSTRACT One third of US children have overweight or obesity; children are developing obesity at higher rates than at any other time in human history. Social determinants of health (SDoH) are strong and especially intractable risk factors for childhood obesity, creating a structural context of stress in early life. Compared to children in high socioeconomic status (SES) households, children in low SES households have 3-4 times higher odds of obesity and elevated biomarkers for chronic stress (cortisol) after adjusting for individual level behaviors. Thus, studies aimed at enhancing resilience to structural SDoH risk factors are critically important for reversing the…

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