Deng Lab

University of Michigan at Ann Arbor

ANATOMY/CELL BIOLOGY

Ann Arbor · United States

NIH-funded
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Research focus

NIH R01 · 2024

Acoustic Tweezing Cytometry for Efficient Neural Differentiation

Project Summary Acoustic Tweezing Cytometry for Efficient Neural Differentiation Human pluripotent stem cells (hPSCs) have been hailed as a promising cell source for treating degenerative, malignant, and genetic diseases, or injuries due to inflammation, infection, and trauma. hPSCs have also been proven as an invaluable discovery tool to study human development and for developing and testing new drugs. However, to fully realize the tremendous potential of hPSCs, the first and perhaps the most critical step is the directed differentiation of hPSCs to specific functional cell types with high efficiency and purity. Motor neurons (MNs) are a specialized class of neurons that reside in the…

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