Froemke Lab

New York University School of Medicine

OTOLARYNGOLOGY

New York · United States

NIH-funded
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NIH R01 · 2024

Neural circuitry of oxytocin signaling for alloparenting behavior

Project Summary Maternal care of offspring requires rapid neurobehavioral changes, including plasticity within circuits specialized for processing infant cues such as crying. Neuroendocrine signals are important for neuroplasticity, including release of the peptide hormone oxytocin. Oxytocin is released from the hypothalamus and is important for childbirth and lactation. Oxytocin also acts in the brain where it is believed to increase the salience of social information, enhancing pair bonding and maternal behavior. Clinical studies suggest that oxytocin is a promising therapeutic agent, with patients sometimes engaging more successfully in social interactions. Although there is a high rate…

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