Frisken Lab

Brigham and Women's Hospital

Boston · United States

NIH-funded
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NIH R01 · 2024

Generating High Quality, High Resolution, Patient-Specific 4D Models of Cerebral Vasculature

Abstract Neurovascular diseases, including stroke, aneurysms, and arteriovenous malformations, can cause devastating and life-threatening injury to the brain. Each year these diseases affect nearly 1 million people in the US. Stroke alone kills more than 130,000 Americans each year. Effective treatment of these diseases requires understanding the cerebrovascular architecture, which is complex and patient specific. Existing clinically available methods for imaging blood vessels in the brain are limited by several factors, including spatial and temporal resolution, the need for ionizing radiation or contrast agents, and the lack of availability of some types of imaging during surgical…

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