Fridman Lab

Johns Hopkins University

OTOLARYNGOLOGY

Baltimore · United States

NIH-funded
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NIH R01 · 2025

Modulation of the Vestibular System Using Prosthetic Direct Current Stimulation

Project Summary The central goal of this project is to advance the therapeutic application and the development of an exciting novel neuroprosthetic technology, Safe Direct Current Stimulation (SDCS). Direct current (DC) compared to biphasic charge balanced pulses normally used by neural prostheses to interface to the nervous system, can more naturally control neural activity. Unlike biphasic current pulses used to excite neurons, DC can excite, inhibit, and modulate sensitivity of neurons. However using DC for implantable prosthetic applications has not been possible due to the DC’s inherent violation of the charge injection safety constraints at the metal electrode interfaces. Safe DC…

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