Fregly Lab

Rice University

ENGINEERING (ALL TYPES)

Houston · United States

NIH-funded
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NIH R01 · 2024

OpenSim Enhancements to Enable Computational Design of Personalized Treatments for Movement Impairments

Abstract Osteoarthritis, stroke, spinal cord injury, traumatic brain injury, and amputation affect roughly 19% of the U.S. adult population, with osteoarthritis and stroke being leading causes of serious long-term disability in adults worldwide. Along with other conditions such as cerebral palsy, Parkinson's disease, and orthopedic cancer, these conditions often significantly impair movement, resulting in substantial societal costs, an increased risk of other serious health conditions (e.g., heart disease and diabetes), a reduction or even loss of independence, and a decreased quality of life. Despite the significance of the problem and the uniqueness of each patient, treatment design for…

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