Franz Lab

Univ of North Carolina Chapel Hill

BIOMEDICAL ENGINEERING

Chapel Hill · United States

NIH-funded
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NIH R01 · 2024

A framework for feasible translation to enhance foot and ankle function in aging and mobility

PROJECT SUMMARY This proposal will address the critical need for new and modifiable targets to enhance mobility and restore independence to those in our rapidly aging population. Due to reduced ankle push-off power, older adults walk slower and with higher metabolic energy cost than younger adults. As our central premise, we contend that hallmark age-associated deficits in push-off intensity during walking have been far too often mistakenly attributed solely to the plantarflexor muscles, and instead originate interdependently with those in the active, passive, and structural regulation of foot mechanical power. This premise paves the way for translational opportunities to augment foot…

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