Alagoz Lab

University of Wisconsin-Madison

SURGERY

Madison · United States

NIH-funded
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NIH R01 · 2024

Estimating and Mitigating Thyroid Cancer Overdiagnosis: A Mathematical Modeling Approach

Project Summary/Abstract This proposal will generate evidence to reduce the overdiagnosis of thyroid cancer in the United States. Overdiagnosis is the identification of a disease that, had it not been detected, would be unlikely to cause symptoms or death during a patient’s lifetime. Overdiagnosis has significant consequences, such as overtreatment with associated side effects and complications, patient anxiety, and increased healthcare costs. Despite a three-fold increase in thyroid cancer diagnoses since the late 1980s, the mortality rate remains stable. Small papillary thyroid cancers, which are rarely lethal, are responsible for virtually the entire increase in incidence. However, it is…

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