Harvard University D/B/a Harvard School of Public Health
MICROBIOLOGY/IMMUN/VIROLOGY
Boston · United States
NIH R01 · 2025
Molecular basis of antibiotic resilience in Mycobacterium tuberculosis
Summary We have identified a novel driver of treatment failure in Mycobacterium tuberculosis, termed antibiotic resilience, where the bacteria have improved recovery after antibiotic exposure. Population genomic and genetic studies implicate a novel transcriptional regulatory network in control of antibiotic resilience, which we will dissect through genomically informed structure-function studies and in treatment models.
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.
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