NIH R01 · 2025
Deciphering the Heterogeneous Response to Influenza by a Multi-Scale Systems Approach
Project Summary Seasonal influenza epidemics, caused by influenza A and B viruses, result in 3–5 million severe cases and 300,000–500,000 deaths globally each year - especially in high-risk groups such as young children, pregnant women, obese individuals, individuals with a compromised immune system, and indigenous populations. The burden of influenza can vary widely between seasons, in part due to characteristics of the circulating viruses, the existing immunity in the population, and the effectiveness of seasonal influenza vaccines against the circulating virus strains. Disease morbidity and mortality increase when a new influenza strain reasserts or jumps the host and becomes capable of…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.