NIH R01 · 2025
Determining modes of dopamine transmission
Project Summary Dopamine system is a key neuromodulator that plays multiple roles in regulating locomotion, activity and motor learning within the striatum. As such dysfunctions in dopamine signaling arise in multiple neurological disorders such as Parkinson’s disease. Despite a wealth of literature at the circuit, system and behavioral level it still remains unknown how dopamine signals mediate transmission and how potentially different signals drive different aspects of motor function and learning. To address this the current proposal will use several novel approaches to examine if different dopamine signals exist and if they do what role they may play in gross motor output and motor…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.