NIH R01 · 2025
Basal Ganglia - Brainstem Networks in the Control of Seizures
Project Summary. Epilepsy is the second most prevalent neurological disorder, affecting approximately 2 million people in the United States. While many patients achieve satisfactory seizure control with pharmacotherapy, a significant proportion (20-40%) have medically intractable seizures. For these patients, identification of novel methods for seizure control is a high priority. One such method may be to harness endogenous seizure suppressive circuits in the brain. Because seizures may have multiple or unknown initiation sites, focal stimulation approaches (e.g., deep brain stimulation [DBS]) that can control seizures originating in diverse brain networks are highly desirable. The…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.