Fontanini Lab

State University New York Stony Brook

NEUROSCIENCES

Stony Brook · United States

NIH-funded
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Research focus

NIH R01 · 2025

Functional role of Gastrin Releasing Peptide (GRP) and GRP expressing neurons in the gustatory cortex

PROJECT SUMMARY It is well-established that neural activity in the rodent gustatory cortex (GC) encodes taste, taste-predictive cues and taste-guided decisions. These neural signals play an important role in guiding behaviors related to taste and consumption. Recent electrophysiological and imaging studies demonstrated that GC can also process interoceptive information pertaining to the homeostatic control of feeding and drinking, with hunger/satiety and thirst/quenching affecting neural activity on both the slow time scale of ongoing activity and the fast time scale of taste- and cue-evoked activity. The GC circuits and neurochemicals involved in processing interoceptive signals as well as…

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