NIH R01 · 2025
Solving longstanding mysteries in plasma triglyceride metabolism
Title of Project: “Solving longstanding mysteries in plasma triglyceride metabolism” PROJECT SUMMARY/ABSTRACT The objective of this Multiple Principal Investigator (PI) R01 grant is to solve persistent mysteries in the molecular physiology of plasma triglyceride (TG) metabolism. The PIs, Loren Fong (UCLA) and Michael Ploug (Finsen Laboratory, Copenhagen), are international leaders in TG metabolism. Fong, a cell biologist and physiologist, discovered that GPIHBP1, an endothelial cell (EC) protein, captures LPL within the interstitial spaces (where it is secreted by parenchymal cells) and moves it to the capillary lumen. Ploug, a physiologist and protein chemist with specialized expertise in…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.