NIH R01 · 2024
QT prolonging medications and sudden cardiac death among individuals on hemodialysis
PROJECT SUMMARY/ ABSTRACT Individuals receiving maintenance hemodialysis (HD) have exceedingly high mortality, driven largely by cardiovascular events. The rate of sudden cardiac death (SCD) in the HD population exceeds that of the general population by more than 20-fold. Risk factors for SCD such as structural heart disease and conduction abnormalities are common among people with end-stage kidney disease, but traditional preventive strategies, such as antiarrhythmic medications and implantable cardioverter defibrillators, do not lower SCD risk in HD patients. However, medication-provoked SCD may be preventable, and, to-date, has been understudied in HD patients. Dialysis patients are…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.