NIH R01 · 2025
Proteomic and Genomic Discovery of Targets for Atrial Cardiopathy-Related Cardiovascular Outcomes
ABSTRACT Atrial fibrillation (AF) is a common arrhythmia associated with serious consequences. Recent evidence suggests that much of the morbidity attributed to AF may be caused by underlying abnormalities in the structure and function of the left atrium, known as atrial cardiopathy. Among individuals free of AF at baseline, measures of atrial cardiopathy are independently associated with incident cardiovascular disease. Additionally, atrial cardiopathy is a potent prognostic marker in higher-risk patients with established cardiovascular disease. However, our limited understanding of the molecular mechanisms that link atrial cardiopathy with clinical disease is a major obstacle to…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.