Florsheim Lab

New York University School of Medicine

INTERNAL MEDICINE/MEDICINE

New York · United States

NIH-funded
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NIH R01 · 2025

Accumulation of micro- and nanoplastic particles in mammalian tissues: a translational study

ABSTRACT The utilization and subsequent disposal of plastics and plastic based products continues to rise exponentially. Current pervasiveness of micro- and nanoplastic particles (MNPs) in the environment results in significant exposure to human populations via inhalation and ingestion. MNP contaminants have been discovered in the air we breathe, the food we eat, and in 81% of tap water samples tested around the globe. Samples taken from human subjects, including our preliminary data, identify MNP deposition in tissues (e.g., lung, heart, blood, thrombi, and placenta) and excreta (e.g., semen, breast milk, bronchoalveolar lavage fluid, and feces). These findings indicate that not only are…

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