Flint Lab

University of California Los Angeles

NONE

Los Angeles · United States

NIH-funded
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NIH R01 · 2024

Combining Voice and Genetic Information to Detect Heterogeneity in Major Depressive Disorder

PROJECT SUMMARY This application aims to advance our understanding of major depressive disorder (MDD) by combining genetic information and analyzing speech patterns of those with MDD to identify subtypes. MDD is the leading cause of disability throughout the world, yet, relative to other common disorders, less is known about its origins. There are less effective treatments and much less is spent on trying to understand how it arises and how to cure it. Current treatments are relatively ineffective, with up 50% of patients refractory and many suffering severe recurrence. Understanding the mechanisms underlying MDD has been recognized as a grand challenge in global mental health. Thus,…

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