Fletcher Lab

University of Tennessee Health Sci Ctr

ANATOMY/CELL BIOLOGY

Memphis · United States

NIH-funded
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Research focus

NIH R01 · 2024

Cholinergic modulation of olfactory coding.

Project Summary Understanding how brain states influence sensory coding is fundamental in advancing our knowledge of the mechanisms by which neural circuits encode sensory information. The basal forebrain cholinergic system has long been implicated in such state changes and has been shown to play a crucial role in the detection, selection, and processing of behaviorally relevant stimuli. However, to date, almost all work regarding cholinergic modulation of olfactory circuits has focused on the effects of acetylcholine on olfactory system neurons while largely ignoring the circumstances that drive cholinergic neuron activity. Thus, very little is currently known regarding the conditions that…

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