Utah State Higher Education System--University of Utah
OPHTHALMOLOGY
Salt Lake City · United States
NIH R01 · 2025
PROJECT SUMMARY Age-related macular degeneration (AMD) is the leading cause of severe vision loss in the developed world. AMD is characterized by progressive degeneration of photoreceptors and the retinal pigment epithelium (RPE) that may be accompanied by the development of macular neovascularization (MNV). MNV gets clinically apparent when these new vessels become ‘exudative’. This exudative stage of ‘neovascular’ AMD can be treated by application of biologics that inhibit vascular endothelial growth factor. Without treatment, exudative MNV typically results in extensive fibrosis with severe central vision loss. Interestingly, there is a growing body of evidence that photoreceptor and RPE…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.
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