NIH R01 · 2024
Brain-Wide Representations of Behavior During Aversive Internal States in C. Elegans
As animals navigate their environments, their nervous systems transition between a wide range of internal states that influence how sensory information is processed and how behaviors are generated. These states of arousal, motivation, and mood typically persist for long durations of time, from minutes to hours, and exert widespread effects across multiple sensory modalities and motor systems. Although most animals organize their behavioral outputs in this state-like fashion, the neural mechanisms that underlie the generation of these states are poorly understood. One prevailing hypothesis to explain how internal states are generated suggests that fast timescale neural dynamics, which…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.