NIH R01 · 2025
Defining the neurocircuit activated by the VMH to control energy expenditure.
PROJECT ABSTRACT While body weight is tightly regulated in healthy individuals, obesity results from failed homeostatic mechanisms that protect individuals from metabolic disease. Obesity already plagues approximately 100 million people and costs approximately $200 billion dollars annually in this country. Thus, it is imperative that we find better ways to treat obesity before this problem gets out of control. The brain contains unexplored potential avenues for obesity treatment. While it has been clear that neural mechanisms can dramatically shift energy homeostasis, these mechanisms have been poorly described to this point. Specialized neurons detect changes in energy status. Because the…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.