Fisher Lab

Univ of Maryland, College Park

BIOMEDICAL ENGINEERING

College Park · United States

NIH-funded
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NIH R01 · 2025

3D Bioprinted Nipple-Areolar Complex Implants

ABSTRACT Over 100,000 women in the United States undergo mastectomy procedures each year due to breast cancer, resulting in loss of breast tissue. One of the key traits of a patient's breast tissue that is often neglected in reconstruction is the nipple areolar complex (NAC). There is no clinically viable solution for NAC reconstruction or regeneration. The long-term goal of this work is to develop a personalized, bioresorbable NAC that will provide patients with the shape of a native nipple projection. To pursue this goal, we have developed a hybrid biomaterial implant system consisting of two complementary polymers that (1) define the architecture of the NAC and (2) encourages tissue…

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