NIH R01 · 2024
The Development and Integration of Early Born SST-Expressing Interneurons in the Cortex
Project Summary In this grant we propose three aims focused on exploring the following: (Aim 1) Determine the efferent target selectivity of granular and infragranular SST cINs and determine the developmental strategy by which this is achieved. (Aim 2) Explore the developmental molecular and cellular basis by which SST cIN diversity is generated. (Aim 3) Identify and validate the SST prototypes during late embryonic and early developmental periods that give rise to the nine SST cIN cell types that populate the mature cortex. A chief goal of my laboratory is to determine cortical interneuron diversity contributes selectively to cortical function and how perturbations in these programs result…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.