Fields Lab

Washington University

PEDIATRICS

Saint Louis · United States

NIH-funded
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Research focus

NIH R01 · 2025

Neurocognitive Effects of Late-Childhood Iron Deficiency Anemia

PROJECT SUMMARY Iron deficiency anemia (IDA) experienced in early childhood causes long-lasting negative consequences on brain development, connectivity and cognition. Given the high prevalence of IDA in infants and toddlers and significant neurocognitive consequences, IDA screening is widely recommended in the first year of life. However, the brain continues to develop throughout childhood, and the incidence of IDA sharply increases again in late-childhood among menstruating females, occurring in 1 of every 16 adolescent females. Of greatest concern, recent studies have found that late-childhood IDA negatively impacts cognitive performance. Anemia results in cerebral metabolic stress with…

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