NIH R01 · 2025
Creation of the Framingham Heart Study Cardiovascular Biobank and Atlas
Abstract Cardiovascular risk factor burden heavily impacts most cardiovascular disease (CVD) events. A longer duration of CVD risk factor exposure is associated with elevated risk of CVD and reduced longevity. The complex phenotypic variation and duration of multimorbidity in individuals results in unique challenges in understanding the underlying pathobiology of CVD. Currently, our knowledge of human cardiac tissue biology in CVD is based upon small numbers of chamber biopsies or postmortem sampling in select diseases, and are largely restricted to White individuals, limiting generalizability. Human cardiovascular tissue multiomics paired with longitudinal clinical, imaging, and CVD risk…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.