NIH R01 · 2025
Mechanisms and functions of temporal coordination in the entorhinal-hippocampal network
PROJECT SUMMARY Episodic memory involves learning and recalling associations between items and their spatio-temporal context. Those memories can be further used to flexibly support different behavioral demands. In this proposal we address the question of how the fine temporal coordination of neuronal activity across entorhinal and hippocampal areas support learning and memory. Oscillatory synchrony in the theta (~5-9 Hz) and gamma (~30- 100 Hz) frequency bands between hippocampus and entorhinal cortices has been implicated in these processes, although the precise mechanisms are not known. The medial (MEC) and lateral (LEC) entorhinal areas are the major source of inputs to the hippocampus.…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.