Fernandez Lab

Georgia Institute of Technology

CHEMISTRY

Atlanta · United States

NIH-funded
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NIH R01 · 2025

Deep Ovarian Cancer Metabolomics

Principal Investigator: Facundo M. Fernández – Deep Ovarian Cancer Metabolomics PROJECT SUMMARY Ovarian cancer (OC) is the 5th leading cause of cancer-related deaths for U.S. women and the deadliest gynecological disease. Lack of symptoms in addition to the deficiency of highly specific biomarkers for detection typically result in only 25% of OC cases being diagnosed at FIGO stage I. High-grade serous ovarian cancer, also known as high-grade serous carcinoma (HGSC), is the most prevalent form of OC, but three rarer histological subtypes also exist—endometrioid, clear cell, and mucinous. An effective screening strategy for early diagnosis would be particularly advantageous since 5-year OC…

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