Feng Lab

New York University School of Medicine

RADIATION-DIAGNOSTIC/ONCOLOGY

New York · United States

NIH-funded
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NIH R01 · 2024

Rapid Motion-Robust and Easy-to-Use Dynamic Contrast-Enhanced MRI for Liver Perfusion Quantification

Project Summary The broad objective of this application is to develop a rapid motion-robust and easy-to-use dynamic contrast- enhanced magnetic resonance imaging (DCE-MRI) framework for liver perfusion quantification and to evaluate its performance in quantitative assessment of hepatocellular carcinoma (HCC), the most prevalent primary malignancy in the liver. Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) using gadolinium-based contrast agents is currently a cornerstone for identifying and characterizing hepatic lesions, including HCC. However, the current clinical use of liver DCE-MRI is limited to visual assessment of the pattern of perfusion in 3-4 multiphasic images…

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