Feldman Lab

University of California, San Francisco

PEDIATRICS

San Francisco · United States

NIH-funded
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Research focus

NIH R01 · 2024

Molecular responses and physiological implications to systemic stimuli in adipocyte progenitor cells

Adipose tissue has important implications for metabolism and general health. It is now well established that, rather than being a passive tissue for energy storage, as it was once perceived, adipose is a dynamic tissue that responds to changing physiological needs and systemic signals as well as secretes a variety of potent hormones with metabolic implications. The primary cell type within adipose tissue is the adipocyte and more recent advances have elucidated that there is heterogeneity in types of adipocytes, including divergent functional properties. Using cellular energetics to classify types of adipocytes defines two broad categories: adipocytes that store energy (‘white’ adipocytes)…

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