Fejerman Lab

University of California at Davis

PUBLIC HEALTH & PREV MEDICINE

Davis · United States

NIH-funded
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Research focus

NIH R01 · 2025

Her2 status of breast cancer in diverse populations: improving genetic prediction and understanding molecular correlates

PROJECT SUMMARY Breast cancer is the most common cancer in women and the second leading cause of cancer death in the United States (US). Although women included in the US Census racial/ethnic categories Hispanic/Latina (H/L) and Asian American/Pacific Islander (AA/PI) have relatively low breast cancer incidence compared to non-Hispanic White (NHW) women, multiple studies have reported a higher proportion of human epidermal growth factor receptor positive (HER2+) tumors in these groups (18-30%) compared to NHWs (14-18%). Expression of HER2 is clinically significant because it determines if a patient can receive targeted treatment. HER2+ disease, independent of hormone receptor (HR) status,…

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