NIH R01 · 2025
Latin America Genomics of Breast Cancer Risk Study (LAGENO-BCR)
SUMMARY/ABSTRACT Breast cancer is a leading cause of death in the U.S. and a major public health burden as one woman out of eight will receive a diagnosis in her lifetime. Advances in DNA genotyping and sequencing technologies have led to the identification of >300 germline variants that contribute to breast cancer risk. However, as of today, large ‘omics’ studies include women of mostly European ancestry even though preliminary evidence indicates that there is a clear benefit in studying genetically diverse samples. A genome wide association study (GWAS) in Hispanic/Latina (H/L) women with one tenth of the number of individuals included in previous studies led to the discovery of…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.