NIH R01 · 2025
A Functional Taxonomy of Cortical Astrocytes
PROJECT SUMMARY/ABSTRACT Recent work has solidified the concept that astrocytes are critical circuit components that regulate neuronal activity, particularly synchronous types of activity. However, it remains unclear how astrocytes encode and integrate neuronal circuit signals to mediate this neuronal synchronization. Moreover, the extent to which single astrocytes function as individual computational units or operate as a syncytial network is not well understood. In the proposed research, we aim to address these gaps in knowledge by uncovering both the mechanisms by which neuronal signals are differentially transmitted to astrocytic networks, and those by which astrocytes feedback to…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.