NIH R01 · 2025
Guided Intracellular Delivery using Precise Area Introduction and Transfection (PAINT)
PROJECT SUMMARY The objective of the proposed project is to develop a method called PAINT (Precise Area INtroduction and Transfection) for highly localized, versatile, and efficient biomolecule delivery for “direct-write” guided administration at spatial resolutions from single cell to hundreds of cells. One current approach that is commonly used to deliver biomolecules to cells involves viral or non-viral transfection. These methods do not offer the ability to target delivery of cargo to a subset of cells. Furthermore, they are limited in which cargoes they can deliver efficiently. In contrast, physical delivery methods offer control over the spatial distribution of cellular modification…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.