Burns Lab

Research focus

NIH R01 · 2025

Transcriptomic Changes during early endometriotic lesion development

PROJECT SUMMARY Endometriosis is a non-malignant disorder defined by the presence of endometrial-like tissue outside the uterus and is associated with debilitating pelvic pain and impaired fertility. Retrograde menstruation is a primary etiologic pathway. The on-average 7-10 years between the onset of symptoms and definitive diagnosis of endometriosis places an enormous emotional and financial burden on both the patient and the healthcare system. Despite the significant health care costs and long-term health risks associated with endometriosis, its molecular etiology remains largely unknown, and non-invasive diagnostic and non-hormonal treatment options remain elusive. Therefore, a critical…

From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.