NIH R01 · 2025
The impact of Left Ventricular Assist Device Implantation on Cerebral Hemodynamics and Cognition
PROJECT SUMMARY The left ventricular assist device (LVAD) has revolutionized care for patients with advanced heart failure, but the impact on cerebral hemodynamics is poorly understood and represents an opportunity to optimize outcomes for this challenging patient population. Given organ scarcity and advances in LVAD technology, the majority of LVADs are now implanted as destination therapy. Neurologic complications have long been respected as the most significant contributor to bad clinical outcomes. Suboptimal brain perfusion increases the risk of stroke, cognitive decline, and brain atrophy, all of which are critical concerns in this patient population. Unfortunately, cerebral blood flow…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.