Diel Lab

University of Illinois at Urbana-Champaign

PATHOLOGY

Champaign · United States

NIH-funded
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NIH R01 · 2024

Novel diagnostic tools and animal model system for study human/animal interface of COVID-19

The ongoing pandemic of COVID-19 is designated by World Health Organization (WHO) as a Public Health Emergency of International Concern. Similarities among ACE2 receptors predict that there are several animals could function as reservoirs for the virus. Recent studies by us and others identified felid animals, including domestic cats, tigers and lions as highly susceptible to SARS-CoV-2 infection. These findings cause great concerns on the potential for human to animal and animal to human transmission, along with the virus mutations that appear as the virus goes back and forth between species. One goal of this study is to design and prepare novel reagents and assays for detection and…

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