NIH R01 · 2025
Multimodal MEAs for Parallel Electrical Recording and Sub-second Neuromodulator Sensing
Abstract It has been highly challenging to scale up non-genetic, sub-second neuromodulator sensing or integrate it with electrical recording. Recently, we discovered that mild annealing dramatically improved the electrochemical stability of electroplated carbon coating and transformed conventional microelectrodes into sensors similar to carbon fiber electrodes with excellent neuromodulator-sensing performance based on fast-scan cyclic voltammetry (FSCV). Compared to previous carbonization strategies such as pyrolysis of polymer and laser- induced graphitization, low-temperature, FSCV-stable carbon coating is directly applicable to microelectrode arrays (MEAs), enabling unprecedented spatial…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.