Fanaroff Lab

University of Pennsylvania

INTERNAL MEDICINE/MEDICINE

Philadelphia · United States

NIH-funded
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Research focus

NIH R01 · 2025

A Randomized Controlled Trial of Gamification and Social Incentives to Increase Adherence to Physical Activity Among Patients with Heart Failure with Preserved Ejection Fraction

PROJECT SUMMARY/ABSTRACT Heart failure with preserved ejection fraction (HFpEF), a syndrome characterized by exercise intolerance due to breathlessness and fatigue, is a major public health problem rising in prevalence. No pharmacologic strategy has been shown to improve exertional symptoms in HFpEF patients, but exercise training is beneficial. For this reason, guidelines strongly recommend that patients with HFpEF engage in regular exercise. Despite this recommendation, physical activity in patients with HFpEF is dismally low, and a recent NHLBI working group identified strategies to increase adoption and adherence to physical activity recommendations among patients with HFpEF as a…

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