Everett Lab

Indiana University Indianapolis

INTERNAL MEDICINE/MEDICINE

Indianapolis · United States

NIH-funded
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NIH R01 · 2025

SKNA as a biomarker for cardiovascular events

PROJECT SUMMARY The objective of this application is to test the hypothesis that skin sympathetic nerve activity (SKNA) can be used as a biomarker for physiological events including predicting neurological recovery during therapeutic hypothermia for cardiac arrest, and to risk stratify patients for recurrence of atrial fibrillation (AF) following catheter ablation. The concept that sympathetic nerve activity (SNA) could be determined from recordings obtained from the skin originated from studies that have shown that sympathetic tone is important in cardiac arrhythmogenesis. The research labs at the Krannert Institute of Cardiology have successfully developed methods to record autonomic…

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