NIH R01 · 2025
Sexual dimorphic circuits in photoperiodic encoding and photic processing
PROJECT SUMMARY/ABSTRACT Light regulates neurological function through circuits that remain poorly defined, and there remains a significant unmet need in understanding photic plasticity in the brain of both sexes. For example, seasonal changes in day length (i.e., photoperiod) modulate sleep, attention, appetite, metabolism, mood, and immune function occur in a large number of people, with up to 80% being women. The suprachiasmatic nucleus (SCN) drives circadian and photoperiodic responses to light, but there is a large gap in our understanding of sex differences in SCN photic and photoperiodic processing. Our preliminary data indicate that circadian and photoperiodic responses differ by…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.