NIH R01 · 2024
Multidimensional investigation of auditory dysfunction in Down syndrome
PROJECT SUMMARY. Individuals with Down syndrome (DS), the genetic condition caused by trisomy 21 (T21), display widespread auditory dysfunction, with current estimates indicating that ~80% of this population may have one or more forms of hearing loss. Despite the obvious importance of hearing for neurodevelopment, speech development, learning, cognition, social integration, inclusion in the workforce, and overall well-being, the mechanisms by which an extra copy of chromosome 21 causes hearing loss are unknown. Therefore, additional research in this area has potential for transformative discoveries that could improve multiple dimensions of development, health, and quality of life in this…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.